Exploring the Biomedical Revolution: A Look at the Work of Frontline Scientists and How They are Changing Medicine - Softcover

No matter what kind of a scientist you are, or even if you are just an interested layman, I suggest you have this book on your bedside table and read a few pages every day before sleeping. It is pleasant reading, beautifully illustrated and provides excellent cultural material which no one should ignore.

Written for a general audience, Exploring the Biomedical Revolution personalizes science in a charming and friendly way. This book is beautifully illustrated, and it is filled with direct quotes and photographs that illustrate the hopes and accomplishments of many young scientists across America. It brings clear explanations from the frontlines of many exciting advances that promise to improve our health. And it proves that lives filled with dreams, challenge, and adventure are still accessible to all those in our society who want to become scientists.

Good science writing plainly demands lucidity and accuracy. But by my reading, the contributors to this book hold out for a higher standard. Science writing, their work attests, must be infused with feeling, too -- with the thrill of discovery, with reverence for nature's beauty and complexity, with hope for the human good that unraveling its secrets confers.

Elegant is the only word I can think of to describe this book. It is elegant science, elegant science writing, and elegant book design. We have come to expect nothing less from the Howard Hughes Medical Institute.

Many titles on biomedicine are inaccessible to lay audiences; not so this book, which focuses on explanations which are easy to understand, yet with plenty of scientific detail added for those involved in health care. Highly recommended.

This book offers an enticing introduction to recent biomedical research.

A vivid example of how biology, history, and medicine interact to focus on human welfare.

The twentieth century will be remembered as an era of great biomedical discoveries: the development of antibiotics and other lifesaving medications, new insights into the genetic code and the workings of the brain, refined techniques for cloning and organ transplantation. In 1953, when James Watson and Francis Crick identified the shape and composition of the DNA molecule, they transformed the science of genetics; today, with the aid of increasingly sophisticated computers and imaging devices, biomedical science continues to advance at a rapid pace. But many of these discoveries seem mysterious to members of the general public who have never heard of x-ray crystallography or are unfamiliar with the ways that genes and proteins direct the workings of the body. Now, from one of the world's most prestigious medical institutions, this clearly written and richly illustrated volume helps to unravel the mysteries, allowing general readers and students to explore biomedical research and to understand its impact on the fight against human disease.

In his introduction, Philip Leder describes a revolution that "rumbles through every area of biomedicine -- immunology, brain chemistry, parasitology, developmental biology -- granting an intimacy with nature's workings, at a deep, molecular level, once unimaginable." Different sections of the book explore different questions: What can the study of fruit flies or worms tell us about our own genetic makeup? How does a cell "decide" to become male or female? How do our eyes perceive color and movement? How does our immune system work to fight disease, and what happens when the system malfunctions?

Exploring the Biomedical Revolution tells the human stories behind the research. We see the scientists' excitement as they develop magnetic imagery to "spy" on the brain's activity. We see competition and cooperation among scientists who work to develop treatments for Lyme disease, sickle cell anemia, and AIDS. We see some creative problem-solving as one scientist inserts the gene for luciferase, a protein from fireflies, into a strain of tuberculosis -- thus producing lab samples that glow in the dark. Throughout, these stories also show the patients' perspective, detailing the symptoms of malaria or cystic fibrosis or showing how the treatment of hemophilia has changed over the years.

Written by leading science writers as a part of the Howard Hughes Medical Institute's public education mission, this inexpensive book stimulates our imagination with numerous illustrations -- a life-sized diagram of a human brain, a dramatically magnified picture of T-cells attacking a cancer cell, computer-generated depictions of the influenza virus. Several of the sections include fold-out charts, including a colorful yet disturbing montage of the different microbes that threaten our health, and a flow chart that shows how scientists work to battle genetic disease. And with the aid of a stereoscopic viewer (included), the book also provides some striking three-dimensional images -- the same computer-generated images that help scientists to understand complex biological structures.

Book Sections:

- Blazing a Genetic Trail

- From Egg to Adult

- Seeing, Hearing, and Smelling the World

- Blood: Bearer of Life and Death

- The Race against Lethal Microbes

- Arousing the Fury of the Immune System

- Finding the Critical Shapes